Reversible DNA micro-patterning using the fluorous effect† †Electronic supplementary information (ESI) available: Experimental procedures and further data. See DOI: 10.1039/c7cc00288b Click here for additional data file.
نویسندگان
چکیده
We describe a new method for the immobilisation of DNA into defined patterns with sub-micron resolution, using the fluorous effect. The method is fully reversible via a simple solvent wash, allowing the patterning, regeneration and re-patterning of surfaces with no degradation in binding efficiency following multiple removal/attachment cycles of different DNA sequences.
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Department of Chemistry, Massachusetts I Avenue, Cambridge, MA, 02139-4307, USA. Department of Chemistry and Chemical Street, Cambridge, MA 02138-2902, USA. EDepartment of Chemistry, Queen's Univer Canada K7L 3N6. E-mail: [email protected] † Electronic supplementary information ( and crystallographic details. CCDC 14695 crystallographic data in CIF or o 10.1039/c6sc01754a Cite this: Chem. Sci., 20...
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