Reversible DNA micro-patterning using the fluorous effect† †Electronic supplementary information (ESI) available: Experimental procedures and further data. See DOI: 10.1039/c7cc00288b Click here for additional data file.

نویسندگان

  • Gabriella E Flynn
  • Jamie M Withers
  • Gerard Macias
  • Justin R Sperling
  • Sarah L Henry
  • Jonathan M Cooper
  • Glenn A Burley
  • Alasdair W Clark
چکیده

We describe a new method for the immobilisation of DNA into defined patterns with sub-micron resolution, using the fluorous effect. The method is fully reversible via a simple solvent wash, allowing the patterning, regeneration and re-patterning of surfaces with no degradation in binding efficiency following multiple removal/attachment cycles of different DNA sequences.

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Rhodium-catalyzed C–H functionalization-based approach to eight-membered lactams† †Electronic supplementary information (ESI) available: Data for new compounds and experimental procedures and theoretical studies on mechanisms. CCDC 979559 and 990983. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc00092k Click here for additional data file. Click here for additional data file.

Laboratory of Molecular Recognition an Zhejiang University, Hangzhou 310027, Zh ac.cn State Key Laboratory of Organometallic C Chemistry, Chinese Academy of Sciences, [email protected] Shanghai Key Laboratory of Magnetic Reson Normal University, Shanghai 200062, P. R. † Electronic supplementary information ( and experimental procedures and theor 979559 and 990983. For ESI and crystallo format s...

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Department of Chemistry, Massachusetts I Avenue, Cambridge, MA, 02139-4307, USA. Department of Chemistry and Chemical Street, Cambridge, MA 02138-2902, USA. EDepartment of Chemistry, Queen's Univer Canada K7L 3N6. E-mail: [email protected] † Electronic supplementary information ( and crystallographic details. CCDC 14695 crystallographic data in CIF or o 10.1039/c6sc01754a Cite this: Chem. Sci., 20...

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عنوان ژورنال:

دوره 53  شماره 

صفحات  -

تاریخ انتشار 2017